Friday, September 17, 2021

Mexican researchers develop stem cell therapy to treat burns

Mexico City, Aug 25 (EFE).- Mexican researchers from the Luis Guillermo Ibarra National Institute of Rehabilitation developed a new stem cell therapy to treat second-degree burns.

The new therapy uses radiosterilized pig skin, stem cells and silver nanoparticles, doctor Roberto Sanchez, who heads the research team, told EFE.

Fotografía cedida el 24 de agosto de 2018, de la colección del doctor Roberto Sánchez, posando en un laboratorio en Ciudad de México (México). Investigadores mexicanos desarrollaron una nueva terapia celular que permite el tratamiento de quemaduras de segundo grado profundo en el Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra de Ciudad de México. EFE

“We started with fibroblast and keratinocyte therapies that already exist and included stem cells, which have the capacity to self-renew. We are specializing in mesenchymal stem cells that we obtain from the adipose tissue of burn patients,” he said.

Although the use of pig skin is a fairly common treatment for burns, as it allows retaining liquids, the innovation that doctor Sanchez and his team have implemented is the use of silver nanoparticles.

“Since one of the complications that burn patients suffer is infection, and considering the fact that the indiscriminate use of antibiotics has created antibiotic-resistant bacteria, we decided to include silver nanoparticles,” he said.

“The use of the nanoparticles, which measure less than 100 nanometers, stabilize the skin’s proteins and kill the bacteria. We use these nanoparticles to coat the pig skin, where the stem cells are,” the physician said.

Another advantage of the treatment developed by Sanchez is that “it avoids immunological rejection and the transmission of infections,” due to the use of the patients’ own stem cells.

The stem cell therapy will help patients with deep second-degree burns on more than 50 percent of their bodies, Sanchez said.

According to the World Health Organization (WHO), some 180,000 deaths are caused by burns each year throughout the world, and non-fatal burn injuries are a leading cause of morbidity.

In Mexico, according to the Secretary of Health, around 200,000 people are treated for their burns each year, and 600 die.